CHITIN-BINDING PROTEINS FROM MORINGA OLEIFERA (MO-CBPS): STRUCTURAL CHARACTERISTICS, ANTIFUNGAL MECHANISMS, AND PROSPECTS FOR APPLICATION IN PLANT IMMUNITY AND PHYTOPATHOGEN CONTROL

Authors

  • MZ SALEEM Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • MJ AKHTAR Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • M NOUMAN Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • K HAIDER Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • SAR SHERAZI Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • S MANZOOR Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • GZ JAHANGIR Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • N HUSSAIN Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author
  • S YOUNAS Centre for Applied Molecular Biology (CAMB), University of the Punjab, Lahore, Pakistan Author

DOI:

https://doi.org/10.64013/bbasrjlifess.v2026i1.56

Keywords:

Moringa oleifera, Chitin Binding Protein, Antifungal, Anti-Inflammatory activity

Abstract

Moringa oleifera contains bioactive chitin-binding proteins (Mo-CBPs) that contribute to plant defense and possess significant biotechnological and therapeutic potential. Several isoforms, including Mo-CBP2, Mo-CBP3 and its variants, and Mo-CBP4, exhibit remarkable thermostability and strong antifungal activity. These proteins inhibit fungal growth through chitin binding, membrane disruption, oxidative stress induction, and metabolic interference. Beyond antifungal functions, Mo-CBPs also demonstrate anti-inflammatory and antinociceptive properties. Their stability, effectiveness, and low cytotoxicity make them promising candidates for crop protection, plant immune enhancement, and pharmaceutical applications. Continued research may support their development as biofungicides and therapeutic agents.

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20-06-2026

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Vol. 2026 No. 1 (2026): Volume-5, Issue-1, 2026 (January to December-Current Issue)

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Copyright (c) 2026 MZ SALEEM, MJ AKHTAR, M NOUMAN, K HAIDER, SAR SHERAZI, S MANZOOR, GZ JAHANGIR, N HUSSAIN, S YOUNAS (Author)

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SALEEM, M., AKHTAR, M., NOUMAN, M., HAIDER, K., SHERAZI, S., MANZOOR, S., JAHANGIR, G., HUSSAIN, N., & YOUNAS, S. (2026). CHITIN-BINDING PROTEINS FROM MORINGA OLEIFERA (MO-CBPS): STRUCTURAL CHARACTERISTICS, ANTIFUNGAL MECHANISMS, AND PROSPECTS FOR APPLICATION IN PLANT IMMUNITY AND PHYTOPATHOGEN CONTROL. Journal of Life and Social Sciences, 2026(1), 56. https://doi.org/10.64013/bbasrjlifess.v2026i1.56

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